en عمومى General مقاله اصیل Original Article <div style="text-align: justify;">Background: Disinfection is performed in our laboratory using sodium hypochlorite, glutaraldehyde, alcohol, or hydrogen peroxide. All these products are known for their harmful side effects on human and ecological health. As a part of the search for new sterilization methods that respect the environment<br> much more, we were interested in studying the antifungal activity of ozone gas on the most isolated fungi in our hospital &ldquo;University Hospital Center Hassani Abdelkader of Sidi Bel Abbes&rdquo;.<br> Methods: This study focused on the antifungal activity of gaseous ozone on the most common fungal isolates in the hospital, with consideration of the duration of the exposure to ozone.<br> Results: The fungicidal effect of ozone gas on molds was more effective compared to its effect on yeasts, it makes it possible to inhibit the reproduction and fungal growth of molds, in particular the filamentous molds and the most commonly isolated dermatophytes. A longer exposure would seem to be more effective.<br> Conclusion: Ozone gas can be a new alternative for sterilization and disinfection techniques, especially filamentous fungi and dermatophytes.<br> <br> &nbsp;</div> Disinfection, Sodium hypochlorite, Ozone, Antifungal, Environment 261 265 http://ehemj.com/browse.php?a_code=A-10-1-301&slc_lang=en&sid=1 Samira Djaroud djaroud_samira@yahoo.fr 100319475328460013488 100319475328460013488 No Department of Chemistry, Faculty of Science, UDL University, Sidi-Bel-Abbes, Algeria Zoubir Belmokhtar zoubir_31@yahoo.fr 100319475328460013489 100319475328460013489 Yes Corresponding author: Laboratory of Plant and Microbial Production and Valorization (LP2VM). University of Science and Technology of Oran. Mohamed Boudiaf (USTOMB) Algeria Yassine Merad yassinemerad8@gmail.com 100319475328460013490 100319475328460013490 No Department of Parasitology-Mycology, Djilali Liabes University of Medicine, Sidi-Bel-Abbes, Algeria Kamel Nassour nass_ka@yahoo.fr 100319475328460013491 100319475328460013491 No Department of Electro-technic, Faculty of Electrical Engineering University, Sidi-Bel-Abbes, Algeria Malika Belkacemi belkacemi_malika@yahoo.fr 100319475328460013492 100319475328460013492 No Department of Hemibiology and Blood Transfusion, Djilali Liabes University of Medicine, Sidi-Bel-Abbes, Algeria Derouicha Matmour DRmatmour24@hotmail.fr 100319475328460013493 100319475328460013493 No Department of Therapeutic Chemistry, Djilali Liabes University of Medicine, Sidi-Bel-Abbes, Algeria Zakaria Merad zmerad79@yahoo.fr 100319475328460013494 100319475328460013494 No Departement of Pathological Anatomy and Cytology, Djilali Liabes University of Medicine, Sidi-Bel-Abbes, Algeria