en عمومى General مقاله مروری Review Article <div style="text-align: justify;">Background: Leachate, containing challenging-to-degrade organic substances and persistent toxins, poses significant environmental concerns. Advanced oxidation processes (AOPs) have emerged as a promising solution for effective leachate treatment. This research provides a comprehensive review of the impact of various AOPs in leachate treatment.<br> Methods: This systematic review was conducted, encompassing commonly used AOPs such as ozone, peroxone, O3/catalyst, Fenton, photo-Fenton, UV/TiO2, photolytic persulfate, O3/UV, and O3/H2O2/ UV. Extensive searches were performed using reputable databases, including EBSCO, PubMed, Web<br> of Science, and Google Scholar. Specific keywords and inclusion/exclusion criteria were applied. Data regarding leachate treatment parameters were meticulously summarized and analyzed using descriptive statistical methods.<br> Results: The efficiency of AOPs in removing leachate organic matter varied, with chemical oxygen demand (COD) removal ranging from 41% to 83% in treatment systems. The order of effectiveness was found to be: O3/UV/H2O2 > photo-Fenton > UV/TiO2 > Fenton > persulfate (PS) > O3/UV > O3/H2O2 > O3/catalyst > ozonation (O3). The highest COD removal efficiency of 83.75% was achieved using the O3/UV/H2O2 AOP approach. The removal efficiency of color also varied, ranging from 32% to 100%, depending on the leachate&rsquo;s characteristics, concentration, and specific treatment process utilized.<br> Conclusion: AOPs, particularly the hybrid approach using O3/UV/H2O2, significantly enhance waste leachate treatment by effectively degrading persistent organic compounds through the generation of hydroxyl radicals. Further research is required to optimize AOPs and improve their efficiency in waste leachate treatment.</div> Advanced oxidation processes, Chemical oxygen demand, Hydroxyl radicals, Leachate treatment, Organic compounds 105 125 http://ehemj.com/browse.php?a_code=A-10-1-328&slc_lang=en&sid=1 Mohammad Ali Zazouli zazoli49@yahoo.com 100319475328460014543 100319475328460014543 No Department of Environmental Health Engineering, School of Health, Health Sciences Research Center, Mazandaran University of Medical Sciences, Sari, Iran Zabihollah Yousefi zyousefi2004@gmail.com 100319475328460014544 100319475328460014544 No Department of Environmental Health Engineering, School of Health, Mazandaran University of Medical Sciences, Sari, Iran Esmaeil Babanezhad esmaeil.babanezhad@gmail.com 100319475328460014545 100319475328460014545 No Department of Environmental Health Engineering, School of Health, Mazandaran University of Medical Sciences, Sari, Iran Reza Ali Mohammadpour mohammadpour2002@yahoo.com 100319475328460014546 100319475328460014546 No Department of Biostatistics, School of Health, Mazandaran University of Medical Sciences, Sari, Iran Alireza Ala ala_alireza@yahoo. com 100319475328460014547 100319475328460014547 Yes Corresponding author: Department of Environmental Health Engineering, School of Health, Health Sciences Research Center, Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran