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:: Volume 9, Issue 3 (Summer 2022) ::
Environ. Health Eng. Manag. 2022, 9(3): 201-211 Back to browse issues page
Measurement of ampicillin and penicillin G antibiotics in wastewater treatment plants during the COVID-19 pandemic: A case study in Isfahan
Mehri Samandari , Hossein Movahedian Attar , Karim Ebrahimpour , Farzaneh Mohammadi , Soudabeh Ghodsi
Corresponding author: Department of Environmental Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran , movahedian@hlth.mui.ac.ir
Abstract:   (1800 Views)
Background: In recent years, the world has faced with the COVID-19 pandemic, followed by a significant increase in the use of antibiotics to control the COVID-19 and other secondary infections. The non-biodegradable characteristics of antibiotics and their residues in the environment leads to increased microbial and drug resistance. Therefore, due to the high importance of antibiotics, two antibiotics, ampicillin and penicillin G, were studied in Isfahan municipal WWTPs.
Methods: Sampling was performed for two months during 13 sampling periods and antibiotics were measured using high-performance liquid chromatography with UV detector (HPLC/UV) instrument.
Results: Ampicillin and penicillin G were identified in all samples taken from the both WWTPs. The average concentration of penicillin G in WWTP E and S at the influent, effluent and its removal efficiency were 1050.54±761.43 μg/L, 52.89±49.27 μg/L, 89.80±19.42%, 2055.12±1788.08 μg/L, 143.01±162.59 μg/L and 82.76±21.85%, respectively. Also, the average concentration of ampicillin in WWTP E and S in the influent (796.44 ± 809.6 and 447.1±322.39 μg/L), effluent (48.94 ± 24.25 and 90.31±75.91 μg/L), and its removal efficiency (86.22 ± 19.84% and 66.85±24.88%) were determined.
Conclusion: In two studied WWTPs, the concentration of antibiotics was higher during the COVID-19 pandemic in comparison with previous studies. The statistical analysis showed that there was no significant relationship between the concentration of antibiotics in WWTPs (P<0.05). Also, the statistical results indicated that the correlation is not significant between removal efficiency of antibiotics and removal efficiency of wastewater main parameters.
Keywords: Anti-bacterial agents, COVID-19, Wastewater, High-pressure liquid chromatography, Ampicillin, Penicillin G
Full-Text [PDF 1113 kb]   (1359 Downloads)    
Type of Study: Original Article | Subject: General
Received: 2022/08/16 | Accepted: 2022/07/1 | Published: 2022/09/19
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Ethics code: IR.MUI.RESEARCH. REC.1398.020

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Samandari M, Movahedian Attar H, Ebrahimpour K, Mohammadi F, Ghodsi S. Measurement of ampicillin and penicillin G antibiotics in wastewater treatment plants during the COVID-19 pandemic: A case study in Isfahan. Environ. Health Eng. Manag. 2022; 9 (3) :201-211
URL: http://ehemj.com/article-1-981-en.html

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Volume 9, Issue 3 (Summer 2022) Back to browse issues page
Environmental Health Engineering And Management Journal Environmental Health Engineering And Management Journal
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