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جلد 8 شماره 3 صفحات 195-187 برگشت به فهرست نسخه ها
Association of urinary triclosan and methyl-triclosan levels with predictive indicators of cardiovascular disease and obesity in children and adolescents in 2020 (case study: Kerman, Iran)
چکیده:   (648 مشاهده)
Background: Exposure of children and adolescents to endocrine disrupting chemicals (EDCs) causes the development of non-communicable diseases. Triclosan (TCS) is a fat-soluble antimicrobial agent, and methyl-triclosan (MTCS) is the predominant metabolite of TCS. The increasing use of consumables TCS (toothpaste, mouthwash, personal care products) in human has raised concerns about human health.
Methods: The urinary concentrations of TCS and MTCS were measured by GC/MS. Lipid profiles (TG, TC, LDL, and HDL), anthropometric parameters (WC, BMI z-score, and BMI), FBS, SBP, and DBP tests were performed on 79 children and adolescents.
Results: Of 79 people included as the study population, 42 subjects (53.16%) were males. Most of the study population as 32 subjects (40.50%) were obese. The mean concentrations of TCS and MTCS in the obese population were 5.47 ± 2.99 and 2.32 ± 1.04 µg/L, respectively. After adjusting for possible confounding factors, the results showed that a one-unit increase in DBP caused a 0.03 units increase in TCS levels in male subjects (P = 0.01). A one-unit increase in DBP also caused a 0.02 units increase in MTCS (P = 0.001). There was a significant relationship between TCS and HDL (OR = 0.90, P = 0.005), LDL (OR = 1.13, P = 0.01), and TG (OR =1.05, P < 0.0001). There was also a significant relationship between MTCS and HDL (OR = 0.88, P = 0.001), LDL (OR = 1.03, P = 0.009), and TG (OR = 1.04, P < 0.0001).
Conclusion: According to the results, there is a relationship between TCS, MTCS, and predictive indicators of cardiovascular diseases and obesity.
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نوع مطالعه: مقاله اصیل | موضوع مقاله: تخصصي
دریافت: 1400/5/11 | پذیرش: 1400/5/10 | انتشار: 1400/7/4
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Ethics code: IR.KMU.REC.1399.258



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Nasab H, Mirzaee M, Ebrahimpour K, Hashemi M. Association of urinary triclosan and methyl-triclosan levels with predictive indicators of cardiovascular disease and obesity in children and adolescents in 2020 (case study: Kerman, Iran). Environ. health eng. manag.. 2021; 8 (3) :187-195
URL: http://ehemj.com/article-1-795-fa.html

Association of urinary triclosan and methyl-triclosan levels with predictive indicators of cardiovascular disease and obesity in children and adolescents in 2020 (case study: Kerman, Iran). مجله مدیریت و مهندسی بهداشت محیط. 1400; 8 (3) :195-187

URL: http://ehemj.com/article-1-795-fa.html



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دوره 8، شماره 3 - ( 5-1400 ) برگشت به فهرست نسخه ها
مجله مدیریت و مهندسی بهداشت محیط Environmental Health Engineering And Management Journal
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